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B.S. – Biochemistry, Iowa State University (2012)
Ph.D. – Biochemistry, University of Minnesota (2018)
As a scientist, I enjoy peering into the deep inner-workings of life as we know it. How have the different chemical and biological systems within ecosystems and within our bodies and minds been connected with each other to overall support the vast array of functions we need to survive? It is only through understanding a very detailed picture of this network that we can then use this knowledge for the betterment of everything around us. We can build this understanding of the chemical nature of life by observing and characterizing changes in the chemical forces at work in biological molecules that ultimately impact their function. These changes in function can then be translated out into changes in the function of cells and on into physiology and health.
Our God is at work in the overarching big-picture themes as well as in even the most excruciating level of detail and if we seek to use our authority over creation for the good of those around us, we must first understand how creation works in an intimate level of detail. By peering into those details we can learn more about the care and intention put into creation and learn how we can better serve those around us.
Edmund AB. (2018). The Role of Post-Translational Modifications and Allostery in the Receptor Guanylyl Cyclases GC-A and GC-B. [Doctoral Dissertation, University of Minnesota]. ProQuest Dissertations Publishing.
Edmund AB, Walseth TF, Levinson NM, Potter LR. (2019) “The Pseudokinase Domains of Guanylyl Cyclase-A and -B allosterically increase the affinity of their catalytic domains for substrate.” Science Signaling. Jan 29;12(566).
Dickey DM, Edmund AB, Otto NM, Chaffee TS, Robinson JW, Potter LR. (2016) “Catalytically Active Guanylyl Cyclase B Requires Endoplasmic Reticulum-mediated Glycosylation, and Mutations That Inhibit This Process Cause Dwarfism.” J Biol Chem. May 20;291(21):11385-93.
Shuhaibar LC, Egbert JR*, Edmund AB*, Uliasz TF, Dickey DM, Yee SP, Potter LR, Jaffe LA. (2016) “Dephosphorylation of juxtamembrane serines and threonines of the NPR2 guanylyl cyclase is required for rapid resumption of oocyte meiosis in response to luteinizing hormone.” Dev Biol. Jan 1;409(1):194-201.
